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I am a postdoc researcher in computational neuroscience at the Institute for Theoretical Biology at Humboldt-Universität zu Berlin. I work in the Computational Neurophysiology group of Susanne Schreiber. |
Research interests:
L. Lemaire, M. Behbood, J. H. Schleimer and S. Schreiber. Integrate-and-fire neuron with potassium dynamics capturing activity-mediated switches in firing regimes, in preparation.
L. Lemaire, M. Desroches, M. Krupa and M. Mantegazza. Idealized multiple-timescale model of cortical spreading depolarization initiation and pre-epileptic hyperexcitability caused by NaV1.1/SCN1A, Journal of Mathematical Biology 86 (1), 92, 2023.
L. Lemaire, M. Desroches, M. Krupa, L. Pizzamiglio, P Scalmani and M. Mantegazza. Modeling NaV1.1/SCN1A sodium channel mutations in a microcircuit with realistic ion concentration dynamics suggests differential GABAergic mechanisms leading to hyperexcitability in epilepsy and hemiplegic migraine, PLOS Computational Biology 17 (7), e1009239, 2021. Code: http://modeldb.yale.edu/267047
O. Chever, S. Zerimech, P. Scalmani, L. Lemaire, A. Loucif, M Ayrault, M. Krupa, M. Desroches, F. Duprat, S. Cestèle and M. Mantegazza. Initiation of migraine-related cortical spreading depolarization by hyperactivity of GABAergic neurons and NaV1.1 channels, The Journal of Clinical Investigation 131 (21), e142203, 2021. Code: http://modeldb.yale.edu/267157
E. L. Carroll, R. Alderman, J. L. Bannister, M. Bérube, P. B. Best, L. Boren, C. S. Baker, C. Constantines, K. Findlay, R. Harcourt, L. Lemaire, P. J. Palsbøll, N. J. Patenaude, V. J. Rowntree, J. Seger, D. Steel, L. O. Valenzuela, M. Watson and O. E. Gaggiotti. Incorporating non-equilibrium dynamics into demographic history inferences of a migratory marine species, Heredity 122 (1), pp. 53-68, 2019.
L. Lemaire, F. Jay, I. Lee, K. Csilléry and M. Blum. Goodness-of-fit statistics for approximate Bayesian computation, arXiv, 2016.
| Since 2022 | Postdoctoral researcher Susanne Schreiber's Computational Neurophysiology group Institute for Theoretical Biology, Humboldt-Universität zu Berlin |
| 2018-21 | PhD in Applied MathematicsInria Sophia Antipolis - Méditerranée
Research
Centre,
France Initiation of cortical spreading depolarization and pre-epileptic hyperactivity in a multiscale mathematical model of NaV1.1 mutations: 
Supervisors: Mathieu
Desroches and Martin
Krupa
Reporters: Gemma Huguet and John Rinzel
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| 2017-18 | MSc in Applied MathematicsUniversitat Politècnica de Catalunya (UPC), Barcelona Thesis: Mathematical modeling of metabolic symbiosis in tumour growth Supervisor: Tomás Alarcón | ||||||||
| 2016-17 | M1 (first year of master) in Applied Mathematics and Statistics Université Claude Bernard Lyon 1 | ||||||||
| 2013-16 |
BSc in Biology
Université Pierre-et-Marie-Curie (UPMC, Paris 6)
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| 2022 | ICMNS parallel session on Dynamical systems for neurological disorders |
| 2021 | MOMI workshop on industrial and applied mathematics |
| 2021 | Member of the Inria Sophia Antipolis PhD Seminars organizing committee |
| 2021 | Master course "Mathematical and computational models in neuroscience", 6h Sorbonne Université - Campus Pierre-et-Marie-Curie (Paris) |
| 2023 | Master course "Models of Neural Systems", 6h Humboldt-Universität zu Berlin |
louisiane.lemaire@hu-berlin.de
Institute for Theoretical Biology
Humboldt-Universität zu Berlin
10115 Berlin
Germany